The company Pharmactive, a pioneer in proven effective phytotherapy, conducts significant research on medicinal plants native to the Mediterranean from the RD laboratories of the Madrid Scientific Park Foundation.
One of its lines of work focuses on saffron raw material, for which Pharmactive has identified and extracted only its bioactive principles with therapeutic efficacy to improve people’s mood. Statistics show that more and more people are turning to natural products for the treatment of stress or anxiety, symptoms associated, for example, with depression, which is considered one of the most diagnosed pathologies today, which is why Pharmactive begins to use this ingredient as the basis of its work.
affron®, a patented saffron extract, both in its formula and therapeutic application, with genetic certification (100% Crocus sativus L.) and 100% stable (3 years).
affron® is presented as the first commercial saffron extract analyzed by High-Performance Liquid Chromatography (HPLC), an objective, reproducible, and reliable analysis method.
Due to its standardization, extraction process, traceability (from cultivation to final ingredient), and concentration, this ingredient is quite different from saffron for everyday use.
Five clinical studies make this ingredient the saffron extract with the greatest scientific support on the market and endorse its effectiveness and safety, with no reported side effects or toxicity. The latest of these confirms its efficacy in adolescents.
A 100% Natural Product Indicated for the Treatment of Anxiety and Depression Symptoms, Now Also for Adolescents
The Journal of Affective Disorders has recently published the first study conducted in Australia on adolescents with symptoms of depression, involving 80 young people aged 12 to 16, and it has been conclusive, showing that affron® significantly improves symptoms associated with depression (such as sadness or anxiety) compared to the placebo group.
Two mechanisms of action stand out for achieving these improvements. On one hand, affron® has a great antioxidant capacity, thus preventing oxidative damage that occurs during long periods of stress and anxiety. On the other hand, it is also a potent inhibitor of neurotransmitter reuptake, increasing the concentrations of serotonin, dopamine, and norepinephrine, all related to mood.